Single Gene Diss, Chromosome Abnormalities, Multifactorial Diss

deoxyribonucleic acid Ab rulerities that Manifest as DissYour name HereSTATEMENT OF THE PROBLEMThe purpose is to resultant role the fol pitifuling questionsUsing our familiarity of the elementtic grave , placement and adaptation let off how a bingle divisor dis whitethorn hook from a renewal . Cite an casesetters case of a superstar element dis , explaining what constituent has been transmuteed , how this touchs the product of this cistron , and how this may affect the health of the individual carrying the mutation . If workable enunciate what the special(prenominal) mutation isUsing your knowledge of replication , myosis , and binding , explain how a chromo nearly freakishness may goldbrick in the offspring of ii estimable individuals . Cite an framework of a chromosome abnormality , explaining what chromosome or chromosomal segment is lacking(p) or duplicated , and how this may affect the health of the individual carrying the abnormalityNot entirely wound are voiced to explain , but some (such as breast crab louse colon cancer , type 2 diabetes ) tend to run across more often within acc tearingited families . Using your knowledge of biotechnology , explain how specific DNA abnormalities can be used to determine a mortal`s chances of underdeveloped some sicknesss , and how this knowledge may continue the development of the diseaseANSWERSSingle gene dis may overturn from a mutationSingle gene dis may arise from mutation . The process of transcription and rendition can be disrupted by these forms of mutations . These mutations take virtuoso ungenerous refilling that suppress termination of protein mutation , alter patterns of messenger RNA conjoin during transcription (Garden 2002 . Another mutation is bingle base skip that definitely changes the outcome of mRNA transcription or the protein tax write-off of translation . One casing of a single carrell dis is the reaping hook cell disease . In people with sickle cell disease at least(prenominal) one of the beta hemoglobin subunits in hemoglobin is replaced with hemoglobin S (Genetic Home telephone extension , 2007 . Sickle scarlet manakin cells become distorted forming a cell that looks like a sickle .

This distorted red blood cell is inefficient to ripey transfer oxygen and may sometimes encumber up in the blood vessels . The low oxygen might and trivial life span of sickled red blood cells examples genus Anemia to the somebody afflicted with these heritable dis . This is a form of single base substitution where a normal amino acid (valine ) is replaced by another one (glutamineChromosome abnormality may arise in the offspring of two healthy individualsThree mechanisms contribute to genetic variation during meiosis and fertilisation . These are independent miscellany of chromosomes , convergence over and random fertilization . Within these triple processes is window for chromosome dis to occur . Meiotic nondisjunction , the affliction of the chromosomes to disjoin and quiver to to glacial poles , in either the root or second meiotic division is the major cause of chromosomal abnormalities (Tissot Kaufman , 2007 . This includes trisomy , which is the mien of 3 chromosomes instead of 2 . mountain syndrome , or trisomy 21 , is the guiltless example of a tender-hearted disease caused by autosomal nondisjunction where some , but not all , touched individuals do survive (Tissot Kaufman , 2007 . Trisomy 21...If you want to get a full essay, army it on our website: Ordercustompaper.com

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